Jul. 07, 2025
A high-performance laboratory chiller can not only protect equipment and improve experimental efficiency, but also ensure experimental safety. This article explains how lab chillers work, their common types, key selection criteria, and usage recommendations across different scenarios to help you choose the most suitable chiller solution for experimental needs.
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Laboratory chillers are generally used for the following purposes.
During the continuous operation of experimental equipment such as reactors, vacuum pumps, X-ray generators, and power supply systems, the internal circuits and structural parts will generate heat. If the heat cannot be taken away in time, the equipment will continue to heat up, causing component aging, performance degradation, and even shortened service life. The chiller uses the refrigerant circulation system to remove excess heat from the equipment in time, so that the equipment is always at the optimal temperature.
Some experiments have safety risks, such as battery testing, chemical reactions, high-voltage power supplies, etc., which may cause gas leakage, thermal runaway, or even explosion at high temperatures. In these high-risk applications, chillers are both auxiliary equipment and important safety guarantees.
Precision equipment such as lasers, mass spectrometers, nuclear magnetic resonance, and electron microscopes have strict requirements on working temperature. Temperature fluctuations affect their accuracy and stability. Moreover, many experiments have very strict temperature requirements.
If the ambient temperature or equipment temperature is unstable, the experimental results will have large errors, and the consistency of the experimental results cannot be guaranteed. The chiller can maintain fluid temperature within ±0.1°C, or even ±0.05°C in some models, achieve fast and stable temperature control, and provide accurate ambient temperature for equipment and experiments.
Air-cooled chillers use fans to discharge the heat of the high-temperature refrigerant gas in the condenser into the air, and do not require a cooling water system. Generally, a modular design is adopted, and all components are integrated in the box, with a compact structure that saves lab space. Because it does not require a cooling tower and a water pump, it has a lower initial cost and less maintenance workload.
However, it is sensitive to ambient temperature, and when the ambient temperature is too high, it will affect the cooling efficiency. It has relatively high requirements for ventilation conditions. The fan will generate a certain amount of noise when running, and it cannot operate at ultra-low noise levels. It is not suitable for large test equipment, nor for long-term high-load operation.
The water-cooled chiller uses cooling water to take away the heat of the refrigerant, and then uses a cooling tower to discharge the heat in the cooling water into the air. So it needs to be equipped with a cooling tower, a water pump and pipes. Its cooling efficiency is higher than that of an air-cooled chiller, it is stable even in high ambient temperatures. Its purchase and maintenance costs are higher than those of air-cooled equipment, but its service life is longer. It is suitable for large experimental platforms.
The Chiller heater combo has both cooling and heating functions, and can automatically activate the cooling and heating modules according to program settings. It has a wider operating temperature range, faster response speed, and higher temperature control accuracy. A chiller heater unit completely replaces two chillers and heaters, saving you space and cost. However, its structure is more complex, the initial investment is higher than that of a chiller that can only cool, and maintenance is more troublesome. It is suitable for experiments that require heating and cooling cycle control.
Before buying a laboratory chiller, you need to consider the following factors.
For conventional experiments, a 5℃~30℃ normal temperature chiller is sufficient. For extreme experiments such as battery and material testing, a low temperature chiller (-40℃) or ultra-low temperature chiller (-80℃) is required. To avoid the high-load operation of the chiller affecting its service life, it is recommended to choose a model with a 10°C buffer beyond your required range.
Cooling capacity refers to how much heat the chiller system can take away. A 5kW chiller can remove up to 5kW of heat per hour, ensuring efficient temperature regulation. If the cooling capacity is too small, the chiller will not work. Excessive cooling capacity will cause the equipment to continue to run at low load, resulting in energy waste.
Under conventional cooling, the temperature control accuracy is ±1℃. Scientific research analysis, drug testing, battery material research, etc. require a chiller with an accuracy of ±0.5℃ or higher.
This is a key parameter that affects the efficiency of the coolant circulation. If the pump pressure is insufficient, the output temperature is difficult to reach the set value.
Common heat transfer media include DI water, glycol-water mixture, and heat transfer oil. They have different physical and chemical properties and need to be carefully selected and proportioned according to factors such as the chiller temperature range, compatibility, and pipe material.
Gas/Liquid Chromatography, UV Spectroscopy, ICP-MS and other equipment require low-noise, high-stability, and high-precision chillers. It is recommended to choose an air-cooled chiller with a closed water system and a silent design.
Reactors, jacket heaters and other equipment require a chiller heater combo with a large temperature control range (such as -20℃~150℃), fast temperature rise and fall, and support for setting temperature curves.
Battery pack and cell testing require a high-precision low-temperature chamber that can operate at a constant temperature for a long time. Since multiple groups of samples may be tested at the same time, it is recommended to choose a multi-channel chiller.
Cooling centrifuges, protein freeze-drying equipment, bioreactors and other equipment require low-noise, high-precision chillers that can run constantly. Compact air-cooled machines with antibacterial materials and filtered water circuits are suitable.
If you are shopping for a laboratory chiller, LNEYA can provide you with professional advice and customized solutions. We have rich experience in the production of laboratory refrigeration equipment. We offer a wide range of models, including air-cooled, water-cooled, and combo units. They support multi-channel, multi-temperature zone, explosion-proof, and safety function expansion to meet a variety of experimental needs.
Contact LNEYA technical consultants to get selection suggestions and solutions.
Semiconductor Chiller Market Overview:
semiconductor chiller Market Size was estimated at 8.12 (USD Billion) in . The Semiconductor Chiller Market Industry is expected to grow from 8.64(USD Billion) in to 14.238 (USD Billion) by . The semiconductor chiller Market CAGR (growth rate) is expected to be around 6.45% during the forecast period ( - ).
Key Semiconductor Chiller Market Trends Highlighted
The Global Semiconductor Chiller Market is projected to witness robust growth, driven by the increasing demand for semiconductor devices and the need for precise temperature control in semiconductor manufacturing. The rising adoption of advanced technologies, such as 5G and IoT, spurs the demand for more powerful and efficient semiconductors, necessitating advanced cooling solutions like semiconductor chillers.Stringent environmental regulations and sustainability initiatives are driving the adoption of energy-efficient cooling systems, fostering the growth of semiconductor chillers that offer reduced energy consumption and greenhouse gas emissions. Additionally, the increasing use of artificial intelligence and machine learning in semiconductor manufacturing processes enhances the accuracy and precision of semiconductor chillers, ensuring optimal temperature control and improving yield rates.
Source: Primary Research, Secondary Research, WGR Database and Analyst Review
Semiconductor Chiller Market Drivers
Increasing Demand for Semiconductor Manufacturing
The global semiconductor industry is experiencing a surge in demand due to the proliferation of electronic devices, including smartphones, laptops, tablets, and IoT devices. This has led to a corresponding increase in the need for semiconductor manufacturing facilities, which require specialized cooling systems to maintain optimal operating conditions. Semiconductor chillers are essential for removing heat generated during the semiconductor manufacturing process, ensuring the precision and efficiency of production. As the demand for semiconductors continues to grow, the market for semiconductor chillers is expected to expand significantly.
Advancements in Semiconductor Technology
The semiconductor industry is constantly evolving, with new technologies and processes emerging at a rapid pace. These advancements, such as the adoption of extreme ultraviolet (EUV) lithography and the development of advanced packaging technologies, require more sophisticated and efficient cooling systems. Semiconductor chillers must be able to meet the demanding requirements of these cutting-edge technologies, providing precise temperature control and high cooling capacity. As the semiconductor industry pushes the boundaries of innovation, the demand for semiconductor chillers capable of supporting these advancements will continue to grow.
Government Initiatives and Industry Investments
Governments worldwide are recognizing the strategic importance of the semiconductor industry and are implementing policies and initiatives to support its growth. These initiatives include financial incentives, research and development funding, and infrastructure investments. Additionally, major players in the semiconductor industry are investing heavily in expanding their manufacturing capacity and upgrading their facilities. These investments create a favorable environment for the semiconductor chiller market, as companies seek solutions to meet the cooling requirements of their advanced semiconductor fabs.
Semiconductor Chiller Market Segment Insights:
Semiconductor Chiller Market Media Insights
The Media segment of the Global Semiconductor Chiller Market exhibited steady growth in recent years, driven by the increasing adoption of advanced semiconductor manufacturing technologies and the rising demand for high-performance computing. In , the Media segment accounted for approximately 28.5% of the global Semiconductor Chiller Market revenue, valued at USD 2.46 billion. It is projected to expand at a CAGR of 6.8% during the forecast period, reaching an estimated valuation of USD 4.23 billion by . Water-Cooled Chillers held a dominant position in the Media segment, capturing over 65% of the market share in .The growing popularity of water-cooled systems can be attributed to their superior cooling efficiency, lower operating costs, and ability to handle higher heat loads compared to air-cooled chillers. Water-cooled chillers are commonly used in large-scale data centers and high-performance computing facilities, where reliable and efficient cooling is crucial. Air-Cooled Chillers, on the other hand, represented a smaller but significant portion of the Media segment, accounting for around 35% of the market share in . Air-cooled chillers offer advantages such as ease of installation, lower maintenance requirements, and suitability for smaller spaces.These factors make them a preferred choice for smaller data centers and edge computing applications. The growth of the Media segment is expected to be driven by several factors, including the increasing demand for cloud computing, artificial intelligence, and machine learning applications. The proliferation of data-intensive technologies such as virtual reality and augmented reality is also fueling the need for high-performance computing and specialized cooling solutions. Additionally, the growing adoption of semiconductor manufacturing technologies such as extreme ultraviolet (EUV) lithography is driving the demand for advanced cooling systems capable of handling the high heat loads generated by these processes.
Source: Primary Research, Secondary Research, WGR Database and Analyst Review
Semiconductor Chiller Market Coolant Type Insights
The Global Semiconductor Chiller Market is segmented by Coolant Type into Deionized Water, Ethylene Glycol, and Propylene Glycol. Deionized water is the most commonly used coolant in semiconductor chillers due to its high heat capacity, low electrical conductivity, and non-toxicity. Ethylene glycol is another popular coolant due to its low freezing point and ability to prevent corrosion. Propylene glycol is similar to ethylene glycol but is less toxic and more environmentally friendly. The Ethylene Glycol segment is expected to grow at a CAGR of 6.30% from to .The Propylene Glycol segment is expected to grow at a CAGR of 6.25% from to . The growth of the Semiconductor Chiller Market is attributed to the increasing demand for semiconductors in various electronic devices such as smartphones, laptops, and tablets. The growing adoption of cloud computing and data centers is also driving the demand for semiconductor chillers as they are used to cool high-performance computing (HPC) systems.
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Semiconductor Chiller Market Cooling Capacity Insights
The Global Semiconductor Chiller Market segmentation by cooling capacity showcases a diverse range of options to cater to varying cooling requirements. 'Below 10 kW' segment held a significant market share in , driven by its wide applicability in small-scale semiconductor manufacturing and research facilities. The '10-50 kW' segment is projected to witness steady growth, owing to its suitability for mid-sized fabs and cleanrooms. '50-100 kW' and '100-200 kW' segments are expected to gain traction in the coming years, driven by the increasing adoption of high-power semiconductor devices and advanced packaging technologies.The 'Above 200 kW' segment is anticipated to experience significant growth, catering to the cooling needs of large-scale semiconductor fabs and data centers.
Semiconductor Chiller Market Control Type Insights
Semiconductor Chillers' control types primarily include PID Control, PLC Control, and Intelligent Control. PID Control offers basic temperature control, suitable for applications with stable operating conditions. PLC Control provides more advanced control capabilities, enabling precise temperature regulation and handling complex processes. Intelligent Control leverages AI algorithms for self-optimization, predictive maintenance, and energy efficiency. In , the Global Semiconductor Chiller Market revenue for PID Control was valued at USD 2.14 billion and is projected to reach USD 3.6 billion by , exhibiting a CAGR of 6.7%.PLC Control held a market share of 32.5% in and is anticipated to reach USD 4.9 billion by , growing at a CAGR of 6.5%. Intelligent Control, with its advanced capabilities, is gaining traction and is expected to grow at a CAGR of 7.1%, reaching USD 2.7 billion by . The rising adoption of intelligent control systems for enhanced efficiency and optimization drives the growth of this segment.
Semiconductor Chiller Market Application Insights
Semiconductor Manufacturing is expected to account for nearly 43% of the Global Semiconductor Chiller Market revenue in , driven by the increasing demand for high-power and high-performance semiconductors. Electronics Assembly is anticipated to hold a significant market share of around 28% owing to the growing adoption of electronic devices and advancements in the consumer electronics industry. Medical Device Manufacturing is projected to witness substantial growth due to the rising demand for advanced medical devices and the need for temperature control during manufacturing processes.Chemical Processing and Pharmaceutical Processing collectively are estimated to contribute approximately 21% to the market, as these industries require precise temperature control to ensure product quality and safety.
Semiconductor Chiller Market Regional Insights
The Global Semiconductor Chiller Market is segmented into five key regions: North America, Europe, APAC, South America, and MEA. North America is the largest regional market, accounting for over 35% of the global Semiconductor Chiller Market revenue. The region's growth is driven by the increasing demand for semiconductor chips from the electronics and automotive industries. Europe is the second-largest regional market, followed by APAC. The APAC region is expected to witness significant growth over the forecast period, owing to the rising demand for semiconductor chips from the consumer electronics and industrial sectors.South America and MEA are relatively smaller regional markets, but they are expected to grow at a steady pace over the forecast period.
Source: Primary Research, Secondary Research, WGR Database and Analyst Review
Semiconductor Chiller Market Key Players And Competitive Insights:
Competitive InsightsThe semiconductor chiller market is characterized by intense competition among established players and emerging entrants. Major players in the market include Danfoss, Thermo Fisher Scientific, and Carrier, who possess a significant market share and a wide distribution network. These companies have a long history of innovation and are well-positioned to meet the growing demand for semiconductor chillers.Leading semiconductor chiller market players actively pursue strategic initiatives such as mergers and acquisitions, product development, and technological advancements to enhance their market position. The industry is driven by the increasing adoption of semiconductors across various sectors, fueling the demand for efficient cooling solutions.Overview of 2 CompetitorsDanfossDanfoss is a Danish multinational company specializing in the design and production of components and systems for various industries, including the semiconductor industry. Its semiconductor chillers are renowned for their reliability, energy efficiency, and innovative design. Danfoss has a global presence with manufacturing facilities in Europe, Asia, and North America.Thermo Fisher ScientificThermo Fisher Scientific is a leading provider of analytical instruments, reagents, and consumables for life sciences and other industries. Its semiconductor chillers are engineered to meet the precise temperature control requirements of semiconductor manufacturing processes. Thermo Fisher Scientific has a strong R&D team and a wide product portfolio, making it a competitive player in the semiconductor chiller market.
Key Companies in the semiconductor chiller Market Include:
Applied Materials
ASML Holding
Brooks Automation
Daifuku
Fujitsu
Hitachi HighTech
IPG Photonics
Jabil
Lam Research
Nikon
SCREEN Holdings
ShinEtsu Chemical
Tokyo Electron
Veeco Instruments
ZEISS
Semiconductor Chiller Market Industry Developments
Recent developments in the global semiconductor chiller market include the growing adoption of advanced semiconductor manufacturing technologies, such as extreme ultraviolet (EUV) lithography and high-volume manufacturing (HVM) of advanced packaging technologies
The increasing demand for high-performance computing (HPC) and artificial intelligence (AI) applications is also driving the need for more efficient and reliable semiconductor chillers
Furthermore, government initiatives in various countries to support the semiconductor industry are expected to provide growth opportunities for the semiconductor chiller market
Key players in the market are focusing on developing innovative and energy-efficient chiller solutions to meet the evolving needs of semiconductor manufacturers.
Semiconductor Chiller Market Segmentation Insights
Semiconductor Chiller MarketMediaOutlook
Semiconductor Chiller MarketCoolant TypeOutlook
Semiconductor Chiller MarketCooling CapacityOutlook
Semiconductor Chiller MarketControl TypeOutlook
Semiconductor Chiller MarketApplicationOutlook
Semiconductor Chiller MarketRegionalOutlook
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